| 引用本文: | 湛建阶,周旭章,邹利鹏,等.3-甲氧基-4-羟基苯甲醛肟的合成.[J].国防科技大学学报,2002,24(2):17-18 ,26.[点击复制] |
| ZHAN Jianjie,ZHOU Xuzhang,ZOU Lipeng,et al.Synthesis of 4-hydroxy-3-methoxyphenyl Oxime[J].Journal of National University of Defense Technology,2002,24(2):17-18 ,26[点击复制] |
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| 3-甲氧基-4-羟基苯甲醛肟的合成 |
| 湛建阶, 周旭章, 邹利鹏, 吴文健 |
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(国防科技大学 航天与材料工程学院，湖南 长沙 410073)
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| 摘要: |
| 以香兰素、盐酸羟胺和强碱为原料，制备出了3-甲氧基-4-羟基苯甲醛肟。影响合成反应过程的因素有：温度、试剂的加入顺序、不同的强碱及三种原料的摩尔比。正交实验后三种原料的最佳摩尔比为1：1.2：1.1，产物的产率达97.4%。文中还对不同酸碱度条件下的此反应机理进行了探讨。通过反应产物熔点的测定及其IR、1HNMR、TIC-MS等的分析，确证了合成产物。 |
| 关键词: 合成 香兰素 3-甲氧基-4-羟基苯甲醛肟 |
| DOI： |
| 投稿日期：2001-10-21 |
| 基金项目: |
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| Synthesis of 4-hydroxy-3-methoxyphenyl Oxime |
| ZHAN Jianjie, ZHOU Xuzhang, ZOU Lipeng, WU Wenjian |
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(College of Aerospace and Materials Engineering, National Univ. of Defense Technology, Changsha 410073,China)
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| Abstract: |
| The synthesis of 4-hydroxy-3-methoxyphenyl-oxime has been made from vanillin, hydroxylamine hydrochloric acid and sodium hydroxide The factors of reaction process include theses,such as temprature, reagents, strong bases and mole rate of three crude materials.The results show that the best mole rate of three reagents is for 1:1.2:1.1,and the product ratio is for 97.4%The reactive process and mechanism of synthesis has been discussed.The synthesis product has been corroborated after the measurement of melting point and analysis of its IR,1HNMR,TIC-MS. |
| Keywords: synthesis vanillin 4-hydroxy-3-methoxyphenyl-oxime |
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