| 引用本文: | 王正华,董蕴源,王勇献.蛋白质相互作用网络的几种聚类方法综述.[J].国防科技大学学报,2009,31(4):81-86.[点击复制] |
| WANG Zhenghua,DONG Yunyuan,WANG Yongxian.Review on Several Clustering Methods in Protein-protein Interaction Network[J].Journal of National University of Defense Technology,2009,31(4):81-86[点击复制] |
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| 蛋白质相互作用网络的几种聚类方法综述 |
| 王正华, 董蕴源, 王勇献 |
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(国防科技大学 并行与分布处理国防科技重点实验室，湖南 长沙 410073)
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| 摘要: |
| 蛋白质相互作用网络是后基因组时代系统生物学研究的重要内容。针对蛋白质相互作用网络中的聚类问题，介绍了几种代表性的聚类分析方法，初步分析了这些方法的特点，指出了当前研究工作的困难与挑战，并对今后的研究方向作了展望。 |
| 关键词: 蛋白质相互作用网络 谱聚类 信息流模拟聚类 整体聚类 |
| DOI： |
| 投稿日期：2008-12-23 |
| 基金项目:国家自然科学基金资助项目(60603054，60773021)；湖南省自然科学基金资助项目(08JJ4021) |
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| Review on Several Clustering Methods in Protein-protein Interaction Network |
| WANG Zhenghua, DONG Yunyuan, WANG Yongxian |
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(Key Laboratory of Science and Technology for National Defense of Parallel and Distributed Processing,National Univ. of Defense Technology, Changsha 410073, China)
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| Abstract: |
| Protein-protein interaction network is one of the research hotspot in post-genome era. Several representative methods of clustering in protein-protein interaction network are reviewed. The characteristics of the methods are summarized and the difficulties and challenge are discussed. Finally, the development prospect is proposed. |
| Keywords: protein-protein interaction network spectral clustering message passing clustering ensemble clustering |
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