On the basis of defining the definite conception of enviromental contamination of the space Station, the contamination sources consist of self-contamination, plume contamination and partical cloud contamination according to the causes of contamination. The respective analytical modes for prediction of potential contamination that would be applied to developing simulation modular for external contamination analysis is presented with its own formation mechanism. For the more serious plume contamination, source overall disposal is suggested to construct a project of modular simulation together with modeling construction, alogrithm, numerical simulation of flowfields and the analysis of the effects of contamination to apply to space station design and to develop an applicable contamination control system.