The Anti-Tactical Ballistic Missile (ATBM) plays a more and more important role in the air defense system, and the intercepting decision is a main step in the intercepting process. In this paper, considering the case of large numbers of offensive objects and the constraint of the interceptive ability of the ATBM, the authors provide a general optimized decision model, using 0-1 integral schedule method, to determine the best intercepting plan.