According to the theory of target-directed deformable warhead, a structural model was designed and an experiment of explosion was carried out. Based on the experiment results, the finite element analytic model was established. By utilizing the code LS-DYNA, the deforming process of the deformable warhead and the projectile process of its fragments were numerically simulated. The results of simulation and experiment show that the density and velocity of the fragments are greatly enhanced in the target direction and the simulation is consistent with experiment.