An integrated thermoelectric generation thermal management system for a regenerative cooling scramjet was proposed. Thermoelectric power generators were integrated in the scramjet structure. The integrated thermoelectric generation thermal management system reduces the fuel flux for cooling, through converting part of the energy by heat conduction on the scramjet structure to electric power. The heat that must be taken away by fuel is decreased and the fuel cooling capacity is indirectly increased. At the same time, high temperature and high pressure fuel also has the capacity for doing work. It flows through a turbine and get additional power output for the use of hypersonic vehicle. A parametric study of the integrated thermoelectric generation thermal management system for scramjet was performed. It is known through performance analysis that the integrated thermoelectric generation thermal management system has excellent potential performance over the conventional regenerative cooling. The fuel flux is reduced while the integrated thermoelectric generation thermal management system gives power output.