The robust flight control based on the generalized extended state observer was investigated to address the problems of parameter uncertainties, external disturbances and flight control with measurement noise. The nonlinear longitudinal dynamics were transformed into the linear-like structure state-space equations of state-dependent coefficients on the basis of the state-dependent Riccati equation control method. According to the control method based on generalized extended state observer, the disturbance compensation gain was designed to estimate and attenuate the external disturbances. Consequently, the state feedback gain and disturbance compensation gain were derived to track the desired angle of attack by solving the state-dependent coefficients and the algebraic Riccati equation on-line. Compared with other control methods, the proposed approach not only is robust with the parameter uncertainties and external disturbances, but also remains perfect in tracking performance with the measurement noise. It has high engineering application value.