For the problem of the existing spare parts supply optimization method cannot consider the life cycle, the life cycle was merged into network design in stakes and it was optimized based on the dynamic characteristics of the spare parts demand. Firstly, the requirement characteristics of spare parts at different stages of life cycle were deeply analyzed. Secondly, the spare parts supply respond time transfer equation was built, and the programming model with the optimization goal of maximum support effectiveness throughout life cycle was established under constraint conditions. Simulation cases indicate that a combination of a variety of spare parts protection model can improve the effectiveness of the life cycle, and the overall optimization of the life cycle can be implemented with more efficient spare parts supply.