In order to make multiple missiles effectively complete the simultaneous attack of maneuvering targets in the presence of communication delay, a fixed-time convergence distributed cooperative guidance law against communication delay was proposed. Based on the framework of fixed time control technology, the guidance law can stabilize the time boundary independent of the initial state of multiple missile system and improved the control efficiency of multiple missile system. A fast non-singular terminal sliding mode and virtual leader were used to realize the guidance law′s robustness against communication delay. The Lyapunov stability theory was used to prove the consistency in fixed time. Simulation results show that under the condition of communication time delay, multiple missiles can effectively attack the target simultaneously based on the designed distributed cooperative guidance law.