M-SiO₂ aerogels catalysts(M=Cu or Co)are prepared by sol-gel process and supercritical drying. The resulting aerogels are characterized using transmission electron microscopy (TEM), XRD and nitrogen adsorption analysis. Their catalytic behavior for CO oxidation has been studied. The results indicate that Cu-SiO₂ or Co-SiO₂ catalysts have high catalytic activity at 100-400℃.