The damage-mitigating and life-extending control (DMLEC) based on multiobjective optimization (MOO) is presented by DMLEC policy analysis and synthesis. The progress of solving DMLEC policy by using nonlinear programming is analysed which combines with the dynamics modelling, the structural analysis of turbine blade and the damage modelling of a certain liquid-propellant rocket engine.Then, the start-up process of the LRE under the control of DMLEC is simulated. The result indicates that the damage of blade is mitigated and the service life of LRE is extended considerably while the system performance is only debased a little.