According to the drawbacks of traditional surrogate model based airfoil optimization, dynamic mesh based airfoil design optimization was studied. Hicks-Henne parameterization method was improved against the drawbacks of unsmooth tailing edge, which was subsequently utilized for the construction of airfoil dynamic mesh. Commercial software Pointwise and Fluent were integrated by secondary development, which automates the adding boundary condition and CFD calculation. The data flows and work flows between commercial software and programs were realized under iSIGHT platform. An airfoil optimization case study shows that the method can significantly improve aerodynamic performance of airfoils, and save massive repeat operations, which is verified an effective and high efficient method of airfoil design optimization. 