Landing conditions of space capsule have a great effect on impact characteristics. Firstly, the analysis and simulation model of space capsule was established and validated according to an available experimental data. Methods for explicit nonlinear kinetics analysis were used to simulate the landing impact process of space capsule. And the significance effect and the influence disciplines of parameters related to landing conditions on impact characteristics were analyzed by the orthogonal test design. Results demonstrate that the vertical velocity, the pitch angle, the heeling angle and their interactions significantly influence the maximum impact acceleration, while the horizontal velocity and the rolling angle rarely influence it. These conclusions can provide important reference to both the ground tests of landing impact as well as the structural analysis and design.