The basic problem of gliding guidance for hypersonic vehicles was proposed, and the difficulties of complicated multiple constraints, maneuver requirements, and parameter perturbation in the course of gliding guidance were analyzed. The corresponding research status at home and abroad was surveyed, and the problems were also pointed out. On this basis, the key problems required to be solved at present in the research of gliding guidance for hypersonic vehicles were presented, and the research hotspots in the methods of future gliding guidance were also pointed out. 