In order to study the influence of TA2-B10 alloy tube on the corrosion characteristics of B10 tube under different galvanic corrosion protection methods, the direct connection, electrical insulation connection and electrical insulation + coating of TA2-B10 tube with a diameter of DN80 were set up in Qingdao Maidao seawater test site. After connect three groups of control pipelines with different galvanic corrosion protection methods, flowing seawater and immersion alternate corrosion tests of 1 m/s, 3 m/s, and 4 m/s were conducted in sequence.After test, three sets of B10 pipelines were cut. Through the pipeline inner surface potential distribution test, the corrosion type of the B10 pipeline under different galvanic corrosion protection methods were analyzed; the potential polarization curve, electrochemical impedance spectroscopy and microscopic characterization were used to analyze the corrosion characteristics of the B10 at a distance of 250 mm from the flange joint under different galvanic corrosion protection methods. Results show that the directly connected TA2-B10 tube is in a galvanic corrosion state, the potential in the B10 terminal is positively shifted and the corrosion is accelerated, and the electrical insulation connection and the insulation+coating connection TA2-B10 tube are in a self-corrosive state. The electrical insulation+coating connection has better insulation effect; the B10 sample under electrical insulation+coating connection protection has the smallest corrosion current density and the most negative self-corrosion potential; the impedance spectra of the three groups of B10 samples all show the characteristics of single capacitive impedance arc, the B10 sample of electrical insulation+coating under the protection of layer connection has greater transmission resistance and film layer resistance; electrical insulation+coating connection can effectively slow down the three corrosion tendencies of pitting, pointed and intergranular corrosion. The above results comprehensively show that the insulation+coating protection method has a better galvanic corrosion protection effect.