In order to optimize the design of satellite constellations with specific area coverage and intensive revisits, a design scheme of regression orbit and co-subsatellite point trajectory constellation was adopted, and a method to optimally solve the satellite constellation orbit parameters by integrating genetic ant colony algorithm with the weight ranking coverage of key areas in specific area was proposed. The design requirements of the regional coverage constellation were analyzed, a regression orbit coverage area model was established, the optimal orbit root number was calculated by using the genetic ant colony algorithm, and all the constellation parameters were solved through using the co-subsatellite point trajectory constellation solution algorithm. The simulation results show that the optimized constellation meets the coverage time and revisit frequency requirements for the area target, and provides focused coverage and revisits of important locations in order of weight, which verifies the feasibility of the algorithm.