Aiming at the difference in the cavitation sensitivity of the control valve at different measuring points of the regulating valve body, study on the difference of cavitation induced vibration and the cavitation sensitivity of different measuring points was carried out. A test platform for cavitation-induced vibration acceleration signal acquisition of regulating valve was built, and the acceleration signals of cavitation vibration of regulating valve at multiple measuring points were simultaneously collected. Two characterization parameters, the acceleration level ratio and the gravity frequency, were proposed. Frequency spectrum of the cavitation vibration signal of regulating valve was divided by the 1/3 octave frequency spectrum, and finally the frequency band most sensitive and location of measuring points to cavitation development was obtained. Results show that the vibration signals of measuring point on the same surface of the regulating valve body are similar, and the signals on different surface are significantly different. Vibration signals of the regulating valve are anisotropic. Development of cavitation extent mainly causes the vibration intensity of the frequency band above the center frequency of 10 000 Hz to increase. It is suitable for monitoring cavitation state of control valve.