In order to study the hydrodynamic ram generated by high velocity fragment impacting fluid-filled container, a set of experiment device and testing method was designed to record the evolution of the cavity inside the container, the pressure changes at different positions in the liquid and the deformation of the front and rear panels. Experimental results show that a circle of cavitation bubbles will appear when the fragments impact the rear panel of the container, and the bubbles rapidly expand radially from the point of impact on the inner surface of the rear panel. In the shock phase of the hydrodynamic ram, large negative pressure appears in the area close to the impact point after the initial shock wave pressure pulse, and the area away from the impact point is not affected by the negative pressure. The fragment impact velocity has little effect on the maximum deformation of the front panel and the deformation range expands along the impact point as the impact velocity increases.