In this paper，based on the general condition monitoring model and strategies，taking vibration signals monitoring for example，two kinds of feature parameters have been extracted to monitor devices and processes of the flexible manufacturing system, the one is the variance of vibration signals，the other is the change rate of coefficients estimation of AR model of vibration signals. The monitoring system has been developed and its operating experiment results indicate the monitoring system is succinct，rapid and reliable. It can satisfy the requirements of the flexible manufacturing environments.