An attitude control method of kinetic energy interceptor under blended operation of lateral thrust and aerodynamic force was developed and a short period movement model of interceptor was presented. A combined control system was designed, using linear quadratic optimal tracking control theory and the fire logic of attitude control missiles. Through analyzing the nonlinear tolerance, a conclusion was drawn that the system has strong robusticity to the thrust bias. Simulation results of attitude control and six-dimension intercept trajectory with lateral jet interaction show that the control method proposed has quick response characteristic and good tracking performance for guidance command, and it can meet the demands of direct interception in the terminal phase.