Aiming at the degradation and failure caused by vibration, temperature cycling and etc in strain balance′s measuring circuit (Wheatstone bridges), a detection method was presented. In the method, the bridge was driven on different nodes at different periods and the responses were measured. The bridge′s parameters were calculated on the basis of the theoretical calculation, and its failure was detected on the basis of the clustering method. A principle prototype was developed and the experiment research was conducted. Experiment results show that the presented method is effective, and it can indeed detect the failure and its test accuracy of bridge resistance can reach 0.2‰. The designed prototype realizes the auto-detection of degradation and failure of strain balance measuring circuit, which costs less time consumption than traditional test method and lifts the available time of the wind tunnel test.