The aerodynamic noise of subsonic flight trajectory is wideband non-stationary noise. A new direction of arrival estimation algorithm based on wavelet function was proposed. The time-frequency analysis method was used to obtain the significant characteristics of the aerodynamic noise. By optimizing the characteristics of space-time spectrum, the target signal in time-frequency domain was optimized to enhance the significance of the target signal in space spectrum, effectively realizing the azimuth angle estimation of the aerodynamic noise of the subsonic flight vehicle finally. The experimental data shows that array signal processing model based on time-frequency analysis can better achieve the azimuth angle estimation of aerodynamic noise of subsonic flight vehicle.