In order to solve the problem of early warning aircraft′s airspace configuration in key target air defense operations, a model of multiple early warning aircraft′s array selection and optimal configuration of aircraft number is constructed. The specific tasks of the early warning aircraft′s air defense operations were determined by analyzing the division of early warning lines for the key targets, and the quantitative model of array selection was constructed. A quantitative model of airspace configuration for parallel and tandem routes of multiple early warning aircraft was proposed on the premise of ensuring its own safety and giving full play to the inherent detection power of early warning aircraft. The example operation results show that the model can compare and analyze the effects of key parameters from the cooperative detection of multiple early warning aircraft in airspace configuration, deployment forces and route pattern selection,which can provide theoretical basis for mission planning of early warning aircraft′s combat troops.